{"id":6551,"date":"2024-01-15T14:48:33","date_gmt":"2024-01-15T14:48:33","guid":{"rendered":"https:\/\/www.writemyessays.app\/blog\/questions\/in-women-between-the-age-of-18-45-with-multiple-sclerosis-does-high-dose-vitamin-d-supplementation-compared-to-placebo-result-in-a-reduction-in-disease-progression-over-a-12-month-period\/"},"modified":"2024-01-15T14:48:33","modified_gmt":"2024-01-15T14:48:33","slug":"in-women-between-the-age-of-18-45-with-multiple-sclerosis-does-high-dose-vitamin-d-supplementation-compared-to-placebo-result-in-a-reduction-in-disease-progression-over-a-12-month-period","status":"publish","type":"questions","link":"https:\/\/www.writemyessays.app\/blog\/questions\/in-women-between-the-age-of-18-45-with-multiple-sclerosis-does-high-dose-vitamin-d-supplementation-compared-to-placebo-result-in-a-reduction-in-disease-progression-over-a-12-month-period\/","title":{"rendered":"In women between the age of 18-45 with multiple sclerosis, does high-dose vitamin D supplementation, compared to placebo, result in a reduction in disease progression over a 12-month period?"},"content":{"rendered":"

 This is the start of a research paper below I give you the research question and PICOT. Please <\/p>\n

Select of one of the papers\/the clinical trial you have found related to the research question\/PICOT and, following the process outlined in the video lecture, conduct your appraisal.<\/span><\/div>\n
Answer the following questions related to <\/span><\/span>each section of the paper.<\/strong> <\/span>After you have answered each question, indicate if you conclude the trial is strong enough to include in your review for the reserch.<\/span>
<\/span><\/div>\n
\n

Research Question:<\/span><\/u><\/b><\/p>\n

 <\/span>In women between
\nthe age of 18-45 with multiple sclerosis, does high-dose vitamin D
\nsupplementation, compared to placebo, result in a reduction in disease
\nprogression over a 12-month period? <\/span><\/p>\n

PICOT Analysis: <\/span><\/u><\/b><\/p>\n

P<\/span><\/b>opulation: Individuals
\nwith Multiple Sclerosis<\/span><\/p>\n

I<\/span><\/b>ntervention: Vitamin D
\nsupplements <\/span><\/p>\n

C<\/span><\/b>omparison: To the individuals
\nwho were given the placebo <\/span><\/p>\n

O<\/span><\/b>utcome: Disease
\nprogression reduction. <\/span><\/p>\n

T<\/span><\/b>imeframe: 12-month
\nperiod. <\/span><\/p>\n

Type of question: Comparative Research <\/span><\/p>\n


<\/span><\/p>\n

This are the questions that need to be answer: <\/p>\n

Title:<\/span><\/strong><\/p>\n

    \n
  1. Does the title clearly communicate the study\u2019s content?<\/span><\/li>\n
  2. Is the title free from sensationalism?<\/span><\/li>\n<\/ol>\n

    Introduction:<\/span><\/strong><\/p>\n

      \n
    1. Have the authors reviewed relevant background literature?<\/span><\/li>\n
    2. Is the trial original?<\/span><\/li>\n
    3. What clinical question is the trial addressing?<\/span><\/li>\n
    4. Is the clinical question expressed in the PICOT format?<\/span><\/li>\n<\/ol>\n

      Methods:<\/span><\/strong><\/p>\n

        \n
      1. How specifically are the methods described?<\/span><\/li>\n
      2. Who were the study subjects?<\/span><\/li>\n
      3. How were the recruited?<\/span><\/li>\n
      4. What were the exclusion criteria?<\/span><\/li>\n
      5. How large was the sample size?<\/span><\/li>\n
      6. Was the sample size calculated ahead of time?<\/span><\/li>\n
      7. Was the trial controlled and what was the control?<\/span><\/li>\n
      8. Was the trial randomized and how was randomization performed?<\/span><\/li>\n
      9. Did the trial use allocation concealment?<\/span><\/li>\n
      10. Was the trial blinded?<\/span><\/li>\n
      11. What were the endpoints or outcomes?<\/span><\/li>\n
      12. Were the results analyzed according to intention to treat or per protocol?<\/span><\/li>\n<\/ol>\n

        Results<\/span><\/strong><\/p>\n

          \n
        1. How good was the randomization?<\/span><\/li>\n
        2. What were the results?<\/span><\/li>\n
        3. What was the dropout rate in each group?<\/span><\/li>\n
        4. Do the figures accurately represent the data?<\/span><\/li>\n<\/ol>\n

          Discussion<\/span><\/strong><\/p>\n

            \n
          1. Do the conclusions follow logically from the results?<\/span><\/li>\n
          2. Do the authors make comparisons to the results of similar studies?<\/span><\/li>\n
          3. Did the authors discuss limitations of the trial.<\/span><\/li>\n<\/ol>\n


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            <\/span><\/p>\n<\/div>\n

            <\/p>\n
            <\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

             This is the start of a research paper below I give you the research question and PICOT. Please  Select of one of the papers\/the clinical trial you have found related to the research question\/PICOT and, following the process outlined in the video lecture, conduct your appraisal. Answer the following questions related to each section of the […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":[],"disciplines":[26],"paper_types":[],"tagged":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/questions\/6551"}],"collection":[{"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/questions"}],"about":[{"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/types\/questions"}],"author":[{"embeddable":true,"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/comments?post=6551"}],"version-history":[{"count":0,"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/questions\/6551\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/media?parent=6551"}],"wp:term":[{"taxonomy":"disciplines","embeddable":true,"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/disciplines?post=6551"},{"taxonomy":"paper_types","embeddable":true,"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/paper_types?post=6551"},{"taxonomy":"tagged","embeddable":true,"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/tagged?post=6551"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}