{"id":22765,"date":"2024-04-25T10:27:23","date_gmt":"2024-04-25T10:27:23","guid":{"rendered":"https:\/\/www.writemyessays.app\/blog\/questions\/can-hsp47-be-used-in-future-medical-treatments-or-is-the-protein-simply-bound-to-serve-as-natures-asprin\/"},"modified":"2024-04-25T10:27:23","modified_gmt":"2024-04-25T10:27:23","slug":"can-hsp47-be-used-in-future-medical-treatments-or-is-the-protein-simply-bound-to-serve-as-natures-asprin","status":"publish","type":"questions","link":"https:\/\/www.writemyessays.app\/blog\/questions\/can-hsp47-be-used-in-future-medical-treatments-or-is-the-protein-simply-bound-to-serve-as-natures-asprin\/","title":{"rendered":"Can HSP47 be used in future medical treatments, or is the protein simply bound to serve as nature&#8217;s Asprin"},"content":{"rendered":"<p><span style=\"cursor: auto; color: inherit;\"><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\">Heat Shock Protein 47 is found in many animals and when reduced, serves as nature&#8217;s potent anticoagulant. That is why bears don&#8217;t get blood clots when hibernating, pigs don&#8217;t get clots after birthing and why people with spinal cord injuries don&#8217;t get clots either. The paper that I need written is a&nbsp; compilation of all research that has been done about Heat Shock Protein 47. The main question that I presented is, &#8220;Can HSP47 be used in future medical treatments, or is the protein simply bound to serve as nature&#8217;s Asprin?<\/span><\/p>\n<p><br style=\"cursor: auto; color: inherit;\"><\/span><\/p>\n<div><span style=\"cursor: auto; color: inherit;\"><span style=\"cursor: auto; color: inherit;\"><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\">Introduction, Methods, and Discussion (150 pts), of those:<\/span><\/p>\n<p><br style=\"cursor: auto; color: inherit;\"><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\">**The questions below are just to guide you \u2013 don\u2019t repeat them in your paper, please. Please, no numbering either**<\/span><\/p>\n<p><br style=\"cursor: auto; color: inherit;\"><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\">&nbsp;<\/span><\/p>\n<p><br style=\"cursor: auto; color: inherit;\"><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\">1) What is your question?<\/span><\/p>\n<p><br style=\"cursor: auto; color: inherit;\"><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Identify the question that you investigated (30)<\/span><\/p>\n<p><br style=\"cursor: auto; color: inherit;\"><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\">&nbsp;<\/span><\/p>\n<p><br style=\"cursor: auto; color: inherit;\"><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\">2) Why it is interesting? Why do we care?<\/span><\/p>\n<p><br style=\"cursor: auto; color: inherit;\"><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\">&nbsp;&nbsp;&nbsp;&nbsp;Elaborate on why you think that this question was interesting and worth pursuing, cite appropriate references (30)<\/span><\/p>\n<p><br style=\"cursor: auto; color: inherit;\"><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\">&nbsp;<\/span><\/p>\n<p><br style=\"cursor: auto; color: inherit;\"><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\">3) What did you\/the authors do to answer the question and why?<\/span><\/p>\n<p><br style=\"cursor: auto; color: inherit;\"><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\">&nbsp;&nbsp;&nbsp;&nbsp;Explain in detail the hypotheses and predictions that you examined\/tested, cite appropriate references (30)<\/span><\/p>\n<p><br style=\"cursor: auto; color: inherit;\"><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\">&nbsp;<\/span><\/p>\n<p><br style=\"cursor: auto; color: inherit;\"><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\">4) What did you\/the authors find?<\/span><\/p>\n<p><br style=\"cursor: auto; color: inherit;\"><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\">Describe what you found. What data did you accumulate, what conclusions you have drawn from these data. Do the conclusions agree with the predictions? Did you find support for your hypotheses? Explain.&nbsp; (30)<\/span><\/p>\n<p><br style=\"cursor: auto; color: inherit;\"><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\">&nbsp;<\/span><\/p>\n<p><br style=\"cursor: auto; color: inherit;\"><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\">5) What has been done in this area?<\/span><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\"><br \/><\/span><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\"><br \/><\/span><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-weight: 400; font-size: 11pt; cursor: auto; color: inherit;\">Describe how your results and conclusions are related to previous research that has been done in this area &#8211; cite relevant references. What are the prevalent hypotheses and explanations for the question that you have investigated? Why? (30)<\/span><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\"><b style=\"font-weight: normal; cursor: auto; color: inherit;\"><br style=\"cursor: auto; color: inherit;\"><\/b><\/span><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-weight: 400; font-size: 11pt; cursor: auto; color: inherit;\">Thienel, Manuela, et al. \u201cImmobility-associated thromboprotection is conserved across mammalian species from bear to human.\u201d Science, vol. 380, no. 6641, 14 Apr. 2023, pp. 178\u2013187, https:\/\/doi.org\/10.1126\/science.abo5044.<\/span><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\"><b style=\"font-weight: normal; cursor: auto; color: inherit;\"><br style=\"cursor: auto; color: inherit;\"><\/b><\/span><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-weight: 400; font-size: 11pt; cursor: auto; color: inherit;\">\u201cHeat shock protein inhibitors.\u201d Topics in Medicinal Chemistry, 2016, https:\/\/doi.org\/10.1007\/978-3-319-32607-8.<\/span><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\"><b style=\"font-weight: normal; cursor: auto; color: inherit;\"><br style=\"cursor: auto; color: inherit;\"><\/b><\/span><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-weight: 400; font-size: 11pt; cursor: auto; color: inherit;\">Ito, Shinya, and Kazuhiro Nagata. \u201cRoles of the endoplasmic reticulum\u2013resident, collagen-specific molecular chaperone HSP47 in vertebrate cells and human disease.\u201d Journal of Biological Chemistry, vol. 294, no. 6, Feb. 2019, pp. 2133\u20132141, https:\/\/doi.org\/10.1074\/jbc.tm118.002812.<\/span><\/p>\n<p style=\"margin-top: 0pt; margin-bottom: 0pt; line-height: 1.38; cursor: auto; color: inherit;\"><span style=\"font-size: 11pt; cursor: auto; color: inherit;\"><span style=\"cursor: auto; color: inherit;\"><br style=\"cursor: auto; color: inherit;\"><\/span><\/span><\/p>\n<p><\/span><br style=\"cursor: auto; color: inherit;\"><\/span><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Heat Shock Protein 47 is found in many animals and when reduced, serves as nature&#8217;s potent anticoagulant. That is why bears don&#8217;t get blood clots when hibernating, pigs don&#8217;t get clots after birthing and why people with spinal cord injuries don&#8217;t get clots either. The paper that I need written is a&nbsp; compilation of all [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":[],"disciplines":[206],"paper_types":[],"tagged":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/questions\/22765"}],"collection":[{"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/questions"}],"about":[{"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/types\/questions"}],"author":[{"embeddable":true,"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/comments?post=22765"}],"version-history":[{"count":0,"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/questions\/22765\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/media?parent=22765"}],"wp:term":[{"taxonomy":"disciplines","embeddable":true,"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/disciplines?post=22765"},{"taxonomy":"paper_types","embeddable":true,"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/paper_types?post=22765"},{"taxonomy":"tagged","embeddable":true,"href":"https:\/\/www.writemyessays.app\/blog\/wp-json\/wp\/v2\/tagged?post=22765"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}