pls use intext citation and add a reference list at the end
pls write according to this outline below ( underline are sections or subsections, bullet point is what need to include) :
Introduction
Molecular architecture of Ion Channels
(unifying multidomain structure)
- multiple α-helical transmembrane domains (TMDs), specific example (some six per unit , some 4 per unit…..)
- the pore domain formed by a loop between two transmembrane segment (e.g. P-loop, xxx, xxx….) , specific example ( size, motif difference)
- gating domain (e.g. voltage-sensing, ligand bind, physical forces or intracellular molecules gate)
- inactivation or regulatory structures
- different type of channel differenit subunit composition
Ion Channels example in Animal Signalling Networks
- Voltage- and Ligand-Gated Ion Channels
- Mechanosensitive Channels: PIEZO Family
- Two-Pore Domain Potassium Channels (K2P)
Ion Channels in Plant Signalling Networks
- Stomatal Regulation and Anion Channels (SLAC1)
- Plant Mechanosensitive Channels
- Kinase and Hormonal Signalling Integration
Comparative Integration of Ion Channels in Animals and Plants
Conclusion